The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 20, 1998
Filed:
Nov. 04, 1994
Applicant:
Inventors:
Charles R Petrie, Woodinville, WA (US);
Rich B Meyer, Woodinville, WA (US);
John C Tabone, Bothell, WA (US);
Gerald D Hurst, Iowa City, IA (US);
Assignee:
EPOCH Pharmaceuticals, Inc., Bothell, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H / ; C07H / ; C07H / ; C07H / ;
U.S. Cl.
CPC ...
536 267 ; 536 245 ;
Abstract
This invention is directed to novel substituted nucleotide bases with a crosslinking arm which accomplish crosslinking between specific sites on adjoining strands of oligonucleotides or oligodeoxynucleotides. The invention is also directed to oligonucleotides comprising at least one of these crosslinking agents and to the use of the resulting novel oligonucleotides for diagnostic and therapeutic purposes. The crosslinking agents of the invention are of the following formula (I'):