The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 20, 1998
Filed:
Sep. 15, 1995
Applicant:
Inventors:
Wolfgang Holzer, Darmstadt, DE;
Ilka von Hoegen, Doffenheim, DE;
Wolfgang Strittmatter, Ober-Ramstadt, DE;
Siegfried Matzku, Zwingenberg, DE;
Assignee:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07K / ; C07K / ; C07K / ;
U.S. Cl.
CPC ...
5303911 ; 5303915 ; 5303917 ; 5303919 ; 514 12 ; 4241811 ; 4241791 ; 4241781 ; 435 697 ; 435 711 ; 536 234 ;
Abstract
The invention provides new immunoconjugates comprising a mono-clonal antibody or a fragment thereof specific for the human EGF-receptor molecule and a member of the chemokine family, preferably selected from the C-X-C family, e.g. lnterleukin-8 (IL-8). The immunoconjugates induce cytotoxic and chemotactic activity and are suitable for a targeted tumor therapy.