The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 20, 1998
Filed:
Jun. 07, 1995
Applicant:
Inventors:
Glenn Francis Pierce, Rancho Santa Fe, CA (US);
Regina Mae Housley, Thousand Oaks, CA (US);
Charles Frederick Morris, Newbury Park, CA (US);
Assignee:
Amgen Inc., Thousand Oaks, CA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K / ; A61K / ;
U.S. Cl.
CPC ...
514 12 ; 514 21 ;
Abstract
Based on extensive in vivo studies in animals, it has now been discovered that KGF stimulates proliferation, growth and differentiation in various cells of epithelial tissue, besides keratinocytes. This better understanding of the biological effects of KGF in vivo enables the use of this polypeptide as a therapeutic agent, suitably formulated in a pharmaceutical composition, for the specific treatment of disease states and medical conditions afflicting tissues and organs such as the dermal adnexae, the liver, the lung, and the gastrointestinal tract.