The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 20, 1998

Filed:

Dec. 05, 1996
Applicant:
Inventors:

Shiladitya DasSarma, Amherst, MA (US);

Fazeela Morshed, Amherst, MA (US);

Elizabeth Stuart, Amherst, MA (US);

Samuel Black, Leverett, MA (US);

Assignee:

University of Massachusetts, Boston, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; C07K / ;
U.S. Cl.
CPC ...
4241881 ; 4241901 ; 4242011 ; 4242041 ; 4242071 ; 4242081 ; 4242341 ; 514-2 ; 530350 ;
Abstract

The invention features a composition that includes a substantially pure recombinant gas vesicles which have at least one heterologous peptide inserted into at one of their structural proteins. The recombinant gas vesicle, when administered to a mammal, is capable of eliciting antibodies which specifically bind to the heterologous peptide. The heterologous peptide can be any peptide against which one wishes to raise antibodies, e.g., a peptide found in the gp12O protein of human immunodeficiency virus (HIV).


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