The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 13, 1998
Filed:
Apr. 05, 1996
Ashoke Kumar, Mandideep, Dist. Raisen, M.P., IN;
Dharmendra Singh, Mandideep, Dist. Raisen, M.P., IN;
Mukesh Jagannath Wani, Mandideep, Dist. Raisen, M.P., IN;
Narendra Sriram Joshi, Mandideep, Dist. Raisen, M.P., IN;
Pravin Sahadev Thombre, Mandideep, Dist. Raisen, M.P., IN;
Ajay Singh Rawat, Mandideep, Dist. Raisen, M.P., IN;
Lupin Laboratories Limited, Bombay, IN;
Abstract
This invention relates to an improved regiospecific process for the synthesis of acyclic nucleosides such as, acyclovir and ganciclovir, anti-viral compounds especially effective against herpes virus, and intermediates thereof starting from dyacylguanine and an alkylating agent, selected from 2-oxa-1,4-butanediol diacetate (OBDDA), 1,4-diacetoxy-3-acetoxymethyl-2-oxa-butane, 1,4-dibenzyloxy-3-acetoxymethyl-2-oxabutane. The reaction is carried out in the absence of an acid catalyst and a solvent.