The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 13, 1998
Filed:
Nov. 21, 1994
Elizabeth Ann Olmsted, Devon, PA (US);
Laura Jeanne Mauro, Ann Arbor, MI (US);
Alan Robert Davis, Wayne, PA (US);
Jack Edward Dixon, Ann Arbor, MI (US);
The Regents of the University of Michigan, Ann Arbor, MI (US);
American Home Products Corporation, Madison, NJ (US);
Abstract
A previously undiscovered transmembrane protein tyrosine phosphatase expressed only in bone and testis, osteotesticular protein tyrosine phosphatase (OST-PTP), has been identified, cloned, sequenced, expressed and subjected to enzymatic analysis. Also, a truncated osteoblast specific form (OST) containing the OST-PTP receptor but lacking the catalytic domain was identified and characterized. Based on the unique expression pattern of OST-PTP and OST during osteogenesis, assays can be used to screen for abnormal bone growth patterns and metabolic bone diseases. Moreover, this novel protein provides a specific target for use in conventional and gene therapies directed at treatment of osteoporosis, osteopetrosis and other bone metabolic disorders.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile