The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 1998
Filed:
Jun. 01, 1988
Applicant:
Inventors:
Lloyd G Mitchell, Bethesda, MD (US);
Carl R Merril, Rockville, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H / ; C12Q / ; C12P / ;
U.S. Cl.
CPC ...
536 253 ; 536 254 ; 536 2541 ; 435-6 ; 435 911 ;
Abstract
The invention provides a process wherein a biotinylated oligonucleotide primer and an oligonucleotide primer which has not undergone biotinylation are used when amplifying a DNA sequence to facilitate separation of the DNA strands following the polymerase chain reaction process. The biotinylation/PCR product is then exposed to a support which will selectively bind the biotinylated strand to allow selective elution of the product.