The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 1998
Filed:
Oct. 24, 1994
Applicant:
Inventors:
Kathleen L Berkner, Seattle, WA (US);
Lars Christian Petersen, Hoersholm, DK;
Charles E Hart, Brier, WA (US);
Ulla Hedner, Malmo, SE;
Claus Bregengaard, Hellerup, DK;
Assignees:
ZymoGenetics, Inc., Seattle, WA (US);
Novo Nordisk A/S, Bagsvared, DK;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
536 232 ; 435212 ; 435226 ; 435325 ;
Abstract
The catalytic active site of Factor VII is modified to produce a compound which effectively interrupts the blood coagulation cascade. The modifications render Factor VIIa substantially unable to activate plasma Factors X or IX. Pharmaceutical compositions of the modified Factor VII are used to treat a variety of coagulation-related disorders.