The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 1998
Filed:
Jun. 20, 1996
Bruno Calabretta, Philadelphia, PA (US);
Donatella Venturelli, Philadelphia, PA (US);
Robert V Martinez, Philadelphia, PA (US);
Thomas Jefferson University, Philadelphia, PA (US);
Abstract
DR-nm23 protein is disclosed. A nucleotide sequence encoding the same and fragments thereof, recombinant expression vectors that comprise the nucleotide sequence, host cell comprising the recombinant expression vectors and methods of making DR-nm23 protein are disclosed. Oligonucleotide molecules comprising a nucleotide sequence complementary to a portion of the nucleotide sequence that encodes DR-nm23 and methods of using the same to inhibit DR-nm23 expression are disclosed. Isolated antibodies that bind to an epitope on DR-nm23 are disclosed. Methods of tracking the progress on chronic myelogenous leukemia and methods of detecting the onset of blast crisis phase in an individual with chronic myelogenous leukemia are disclosed.