The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 1998
Filed:
Jun. 07, 1995
Gerd Grieninger, New York, NY (US);
Yiping Fu, New York, NY (US);
Yan Cao, Valhalla, NY (US);
Mohamad Zaher Ahadi, Paterson, NJ (US);
Bohdan J Kudryk, Hillsdale, NJ (US);
The New York Blood Center, Inc., New York, NY (US);
Abstract
The invention provides nonspecific antibodies which are specifically reactive with the .alpha..sub.E subunit of fibrinogen or a fragment thereof, but not with other portions of the fibrinogen molecule. The invention also provides anti-.alpha..sub.E probes, including nonspecific anti-.alpha..sub.E antibodies which have been detectably labeled. In addition, the invention provides methods of using the nonspecific antibodies for detection of the .alpha..sub.E subunit and fragments thereof, as well as reagents and kits for performing the methods. Diagnostic methods for determining information associated with atherogenesis and/or thrombogenesis, as well as for determining information associated with pregnancy status or outcome. The invention further provides continuous cell lines which produce monospecific anti-.alpha..sub.E antibodies.