The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 06, 1998

Filed:

Mar. 26, 1992
Applicant:
Inventors:

Joseph G Sodroski, Medford, MA (US);

William A Haseltine, Canbridge, MA (US);

Craig D Furman, Nashua, NH (US);

Udy Olshevsky, Remath-Oan, IL;

Eirik Helseth, Trondheim, NO;

Richard Wyatt, Tewksbury, MA (US);

Markus Thali, Brookline, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07K / ; C07K / ;
U.S. Cl.
CPC ...
4241881 ; 4242041 ; 4241841 ; 4241081 ; 530395 ; 530350 ;
Abstract

Immunogenic peptides containing amino acid residues which define a binding site to a CD4 receptor are disclosed. Antibodies to these peptides are also disclosed. Methods of reducing the ability of a gp120 env protein to bind to CD4 are also disclosed. Methods of treatment and prophylaxis using these antibodies and peptides are also described.


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