The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 29, 1998

Filed:

Nov. 14, 1996
Applicant:
Inventors:

Rajesh Patel, Redwood City, CA (US);

Lyle M Bowman, Pleasanton, CA (US);

Peng Shen, Hayward, CA (US);

Assignee:

InSite Vision Incorporated, Alameda, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
514413 ; 514567 ; 514570 ; 514912 ;
Abstract

Topical ophthalmic compositions for treatment of the eye are provided which comprise aqueous mixtures of a non-steroidal agent having a pKa, a pH, and a concentration of agent chosen so as to maintain at least a therapeutic amount of the agent in suspension and a therapeutic amount of the agent in solution. A method for treating diseases of the eye, including inflammation, is also provided by topically applying such aqueous mixtures to eyes in need of treatment, whereby the therapeutic amount of the drug in solution has an immediate therapeutic effect at full concentration, and the therapeutic amount of drug in suspension has a delayed therapeutic effect by release from the suspension over a period of time by reason of dissolution kinetics.


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