The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 22, 1998
Filed:
May. 24, 1995
Applicant:
Inventors:
Siegfried Benjamin Christensen, IV, Philadelphia, PA (US);
Paul Elliot Bender, Cherry Hill, NJ (US);
Cornelia Jutta Forster, Bensalem, PA (US);
Assignee:
SmithKline Beecham Corporation, Philadelphia, PA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07C / ;
U.S. Cl.
CPC ...
514520 ; 514521 ; 514523 ; 558426 ; 558430 ;
Abstract
##STR1## Novel cyclohexanes of formulas (I) and (II) are described herein. They inhibit the production of Tumor Necrosis Factor and are useful in the treatment of disease states mediated or exacerbated by TNF production; these compounds are also useful in the mediation or inhibition of enzymatic or catalytic activity of phosphodiesterase IV.