The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 1998
Filed:
Sep. 08, 1994
I Charles Pathirana, San Diego, CA (US);
Christina S Berger, San Diego, CA (US);
Robert B Stein, San Diego, CA (US);
William Fenical, Del Mar, CA (US);
Todd K Jones, Solana Beach, CA (US);
Lawrence G Hamann, San Diego, CA (US);
Michael G Johnson, San Diego, CA (US);
Luc Farmer, La Jolla, CA (US);
Ligand Pharmaceuticals Incorporated, San Diego, CA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
Non-steroidal compounds which are high affinity, high specificity ligands for progesterone receptors are disclosed. The compounds include synthetic derivatives of cyclocymopol and its diastereomers, spectroscopically and chromatographically pure (3R)-cyclocymopol monomethyl ether, which functions as a progesterone receptor antagonist, and spectroscopically and chromatographically pure (3S)-cyclocymopol monomethyl ether, which functions as a progesterone receptor agonist. Also disclosed are methods for employing the disclosed compounds for modulating processes mediated by progesterone receptors and for treating patients requiring progesterone receptor agonist or antagonist therapy.