The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 1998
Filed:
Apr. 01, 1997
Alexander A Klibanov, Newton, MA (US);
Kim Lewis, Newton, MA (US);
Anthony Ferrante, Medford, MA (US);
Catherine L Coyle, Mendham, NJ (US);
Gerben Zylstra, Roosevelt, NJ (US);
Michael S Logan, Phillipsburg, NJ (US);
Matthew J Grossman, Flemington, NJ (US);
Exxon Research and Engineering Company, Florham Park, NJ (US);
Abstract
The present invention includes microorganisms that are resistant to non-aqueous solvents. In addition, the organisms of interest are able to grow and/or carry out various organic (e.g. hydrocarbon) transformations in non-aqueous/aqueous mixtures. The invention also includes a gene which encodes an enzyme, hydroperoxide reductase, which renders the host microorganism resistant to many organic solvents. The invention also includes the operon which includes the mutant gene and the ahpF gene which encodes an NAD(P)H dehydrogenase. The invention also includes a plasmid vehicle and a host microorganism containing these genes. The invention also includes cloning the genes encoding for solvent-resistance into other organisms rendering them solvent-resistant. In addition, the genes encoding for a specific organic or hydrocarbon transformation are placed into the solvent resistant microorganism.