The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 1998

Filed:

Aug. 27, 1996
Applicant:
Inventors:

Paul Hebeisen, Basel, CH;

Ingrid Heinze-Krauss, Schliengen, DE;

Hans Richter, Grenzach-Wyhlen, DE;

Valeri Runtz, Rixheim, FR;

Henri Stalder, Basel, CH;

Urs Weiss, Pratteln, CH;

George Petros Yiannikouros, Westfield, NJ (US);

Assignee:

Hoffmann-La Roche Inc., Nutley, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514202 ; 514206 ; 514225 ; 540221 ; 540222 ; 540227 ; 540225 ;
Abstract

The present invention relates to compounds of formula I ##STR1## wherein R.sup.1 is a group selected from 2-, 3-, and 4-hydroxyphenyl, 3-nitrophenyl, and 3-fluoro-4-hydroxyphenyl; as well as readily hydroyzable esters thereof, pharmaceutically acceptable salts of said compounds and hydrates of the compounds of formula I and of their esters and salts.


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