The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 1998

Filed:

Jul. 07, 1995
Applicant:
Inventors:

Robert I Lehrer, Santa Monica, CA (US);

Sylvia S Harwig, Woodland Hills, CA (US);

Vladimir N Kokryakov, St. Petersburg, RU;

Assignee:

University of California, Los Angeles, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A01N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
514 13 ; 530326 ; 424405 ; 536 235 ; 435 691 ; 4352523 ; 4353201 ; 935-9 ; 935 27 ; 935 66 ;
Abstract

Peptide-based compounds containing four invariant cycteine residues which have been optionally oxidized to contain two intramolecular disulfide bonds, or modified forms where the cysteines are replaced are useful as preservatives and in preventing, treating, or ameliorating viral or microbial infection in animals and plants, and in inactivating endotoxin. These compounds, in one embodiment, are of the formula: ##STR1## and the N-terminal acylated and/or C-terminal amidated or esterified forms thereof, which is either in the optionally -SH stabilized linear or in a cystine-bridged form


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