The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 1998

Filed:

Apr. 15, 1996
Applicant:
Inventors:

Calvin Bruce Harley, Palo Alto, CA (US);

Nam Woo Kim, San Jose, CA (US);

Scott Lawrence Weinrich, Redwood City, CA (US);

Assignee:

Geron Corporation, Menlo Park, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q / ; C12P / ; C07H / ;
U.S. Cl.
CPC ...
435-6 ; 435 915 ; 435 9152 ; 435810 ; 435183 ; 435184 ; 435194 ; 435 912 ; 536 2431 ; 536 2433 ; 935-8 ; 935 78 ;
Abstract

Telomerase activity in a sample can be measured using a two reaction protocol. The first reaction involves the formation of telomerase substrate extension products from a telomerase substrate. The second reaction involves replication of the telomerase substrate extension products and/or amplification of signal generated by a bound probe. The presence of telomerase activity in a human somatic tissue or cell sample is positively correlated with the presence of cancer and can be used to diagnose a disease or other conditions of medical interest, as well as the course of disease progression or remission in a patient.


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