The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 1998

Filed:

Feb. 09, 1995
Applicant:
Inventors:

Can B Hu, Irvine, CA (US);

Minh T Ma, Santa Ana, CA (US);

Than Nguyen, Huntington Beach, CA (US);

Richard Rhee, Diamond Bar, CA (US);

Keith Myers, Lake Forest, CA (US);

Assignee:

Baxter International Inc., Deerfield, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M / ; C12N / ;
U.S. Cl.
CPC ...
435-11 ; 435240241 ; 4352831 ; 4352841 ; 4352972 ; 600 36 ; 623-1 ;
Abstract

An apparatus for sodding onto the inner lumenal surface of a synthetic graft of harvested and concentrated microvessel endothelial cells from liposuctioned fat tissues, which harvested cells are formed into a 'pellet' of isolated endothelial cells in loose aggregations, includes a sodding tube having a single rigid outer wall bounding a sodding chamber. A filter pack assembly is provided to communicate the pellet of cells from a processing vessel to the graft. This filter pack assembly includes a series of successively finer filter members cooperatively defining a series of turbulent-flow chambers in which aggregations of cells too large to pass through a particular filter are exposed to liquid flow turbulence which is effective to break up the aggregations. A check valve assembly ensures that liquid flow is unidirectional so that sodding of the cells onto the inner lumenal surface of the graft is not interfered with by possible liquid reflux, and sodded cells are similarly not dislodged from the graft by such liquid reflux.


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