The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 08, 1998
Filed:
May. 31, 1995
Applicant:
Inventor:
Alfred Pollak, Toronto, CA;
Assignee:
Resolution Pharmaceuticals Inc., Mississauga, CA;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61M / ;
U.S. Cl.
CPC ...
424-169 ; 424-111 ; 424-165 ; 530300 ; 530328 ; 530329 ; 530330 ; 534 14 ;
Abstract
Compounds useful for high resolution diagnostic imaging incorporate an imaging agent having a chelator that is linked by a metal-cleavable bond to a ligand that has affinity for a site removed from the site of diagnostic interest. Upon labelling, the ligand is cleaved leaving the labelled imaging agent free to localize at the site of diagnostic interest unhindered, while the ligand and any unlabelled imaging agent is sequestered to the removed site. By sequestering unlabelled imaging agent, the labelled imaging agent does not compete to occupy the site of interest, resulting in images of enhanced resolution.