The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 25, 1998

Filed:

Apr. 06, 1995
Applicant:
Inventors:

Cheryl A Cathey, Gaithersburg, MD (US);

Tom Saul, El Granada, CA (US);

Nicole D Bloom, San Francisco, CA (US);

Hans O Ribi, Hillsborough, CA (US);

Henry L Schwartz, San Francisco, CA (US);

Jeffrey B Langford, Corvallis, OR (US);

David J Paul, Scotts Valley, CA (US);

Assignee:

Biocircuits Corporation, Sunnyvale, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N / ; G01N / ; G01N / ;
U.S. Cl.
CPC ...
435-79 ; 422 55 ; 422 57 ; 422 58 ; 422 61 ; 435-792 ; 435-793 ; 435-794 ; 4352871 ; 4352872 ; 4352884 ; 4352885 ; 4352887 ; 435810 ; 436514 ; 436518 ; 436524 ; 436527 ; 436528 ; 436164 ; 436172 ; 436537 ; 436805 ; 436807 ; 436808 ; 436810 ;
Abstract

A device and method for its use in diagnostic assays are provided. The device comprises at least one assay path, where an assay path includes a main flow path and at least one side reagent channel. The main flow path begins at a sample addition port, continues through a main reagent area into an incubation area and ends in a waste area. In fluid communication with the main flow path is at least one side reagent channel that begins at a liquid addition port, continues through a side reagent area and ends in said main channel at a region between the main reagent and waste areas, usually upstream from the incubation area. Agitation means may be included in at least one of the main and side reagent areas and/or the incubation area. At least one fluid interruption means located at various positions along the main and side reagent channels upstream from the incubation area provide for control over reagent interaction and fluid flow through the device. Applications in which the device finds use include diagnostic assays employing signal producing systems based on the interactions of specific binding pair members, where an optical signal is related to the presence of analyte.


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