The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 25, 1998
Filed:
May. 24, 1995
Keith E Dionne, Rehoboth, MA (US);
Dwaine F Emerich, Providence, RI (US);
Diane Hoffman, Cambridge, MA (US);
Paul R Sanberg, Spring Hill, FL (US);
Lisa Christenson, New Haven, CT (US);
Orion D Hegre, Green Valley, AZ (US);
David W Scharp, St. Louis, MO (US);
Paul E Lacy, Webster Grove, MO (US);
Patrick Aebischer, Lutry, CH;
Alfred V Vasooncellos, Cranston, RI (US);
Michael J Lysaght, Greenwich, RI (US);
Frank T Gentile, Warwich, RI (US);
Abstract
A method of providing a biologically active molecule or metabolic or immunologic function to a patient, comprising implanting into the body of the patient at least one immunoisolatory vehicle comprising a core comprising a volume in excess of 1 .mu.l and at least about 10.sup.4 living cells dispersed in a biocompatible matrix formed of a hydrogel or extracellular matrix components, said cells being capable of secreting a biologically active product or of providing a metabolic or immunologic function to the patient; and an external jacket surrounding said core, said jacket being formed from a thermoplastic or hydrogel, said jacket being free of said cells projecting externally therefrom, said jacket being biocompatible and having a molecular weight cutoff permitting passage of molecules between the patient and the core through said jacket to provide said biologically active product of function.