The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 18, 1998
Filed:
Jun. 07, 1995
Applicant:
Inventors:
Michael Zasloff, Merion Station, PA (US);
Ann Shinnar, Teaneck, NJ (US);
William Kinney, Churchville, PA (US);
Mark Anderson, Norristown, PA (US);
Jon Williams, Robbinsville, NJ (US);
Michael McLane, Lansdale, PA (US);
Assignee:
Magainin Pharmaceuticals Inc., Plymouth Meeting, PA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
514182 ;
Abstract
Aminosterol compounds are described that are useful as inhibitors of the sodium/proton exchanger (NHE). Methods of using such aminosterols compounds are also disclosed, including those employing compounds that are inhibitors of a spectrum of NHEs as well as those using compounds that are inhibitors of only one specific NHE. Advantageous screening techniques and assays for evaluating a compound's therapeutic activity are also disclosed.