The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 11, 1998
Filed:
Aug. 08, 1996
Applicant:
Inventors:
Stephen E de Laszlo, Rumson, NJ (US);
Nigel J Liverton, Harleysville, PA (US);
Gerald S Ponticello, Lansdale, PA (US);
Harold G Selnick, Ambler, PA (US);
Nathan B Mantlo, Lafayette, CO (US);
Assignee:
Merck & Co., Inc., Rahway, NJ (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; C07D / ; C07D / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514318 ; 514326 ; 514327 ; 514330 ; 514333 ; 514347 ; 514352 ; 514354 ; 514427 ; 546184 ; 546193 ; 546208 ; 546216 ; 546223 ; 546244 ; 546248 ; 548518 ; 548530 ; 548541 ; 548564 ;
Abstract
The present invention addresses 2-substituted aryl pyrroles, as well as compositions containing such compounds and methods of treatment. Cytokine mediated diseases refers to diseases or conditions in which excessive or unregulated production or activity of one or more cytokines occurs. Interleukin-1 (IL-1), Interleukin-6 (IL-6), Interleukin-8 (IL-8) and Tumor Necrosis Factor (TNF) are cytokines which are involved.