The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 11, 1998
Filed:
Mar. 02, 1994
Applicant:
Inventors:
Donald J Sarubbi, Bronxville, NY (US);
Andrea Leone-Bay, Ridgefield, CT (US);
Duncan R Paton, Purdys, NY (US);
Assignee:
Emisphere Technologies, Inc., Hawthorne, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
424 854 ; 424 852 ; 4241411 ; 4241841 ; 424465 ; 424474 ; 424489 ; 424491 ; 424499 ; 514-2 ; 514 12 ; 514 21 ; 514773 ;
Abstract
The present invention relates to an oral drug delivery system, and in particular to modified amino acid derivatives for use as a delivery system of sensitive agents such as bioactive peptides. The modified amino acid derivatives can form non-covalent mixtures with active biological agents and in an alternate embodiment can releasably carry active agents. These mixtures are suitable for oral administration of biologically active agents to mammals. Methods for the preparation of such amino acids are also disclosed.