The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 1998

Filed:

May. 24, 1996
Applicant:
Inventors:

Brenda Baker, Carlsbad, CA (US);

C Frank Bennett, Carlsbad, CA (US);

Kevin P Anderson, Carlsbad, CA (US);

Assignee:

Isis Pharmaceuticals, Inc., Carlsbad, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H / ; C07H / ; C12Q / ;
U.S. Cl.
CPC ...
536 245 ; 536 231 ; 536 2431 ; 536 2433 ; 435-6 ; 435 911 ;
Abstract

Compositions and methods are provided for inhibiting the translation of a capped target mRNA. Antisense oligomers of the invention are targeted to the 5' cap region of the target mRNA and include oligonucleosides, PNAs, or oligonucleotides modified at the 2' position of the sugar. Preferably said oligomers inhibit protein translation directly via interference with ribosome assembly.


Find Patent Forward Citations

Baker, Brenda. (1998). Antisense inhibition of icam-1, e-selectin, and cmv ie1/ie2 (U.S. Patent No. 5789573). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5789573

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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