The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 1998

Filed:

Jun. 07, 1995
Applicant:
Inventors:

Andreas Sommer, Danville, CA (US);

Yasushi Ogawa, Pacifica, CA (US);

Peggy Tao, San Jose, CA (US);

Assignee:

Celtrix Pharmaceuticals, Inc., Santa Clara, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K / ; C07K / ; C07K / ; C12N / ;
U.S. Cl.
CPC ...
530351 ; 530350 ; 530324 ; 530344 ; 530399 ; 530408 ; 530412 ; 435 695 ; 4351723 ;
Abstract

The present invention provides a novel method for refolding insulin-like growth factor I (IGF-I) and insulin-like growth factor binding protein 3(IGFBP-3). The method involves mixing of IGF-I and IGFBP-3 together in a cofolding reaction. The inventive cofolding method results in substantially higher yields of correctly folded protein for both molecules and alters the kinetics of refolding. The method includes the production of correctly folded IGF-I, IGFBP-3, and/or IGF-I/IGFBP-3 complex.


Find Patent Forward Citations

Sommer, Andreas. (1998). Method of producing insulin-like growth factor-i (igf-i) and (U.S. Patent No. 5789547). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5789547

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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