The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 04, 1998
Filed:
Oct. 12, 1994
Applicant:
Inventors:
Edmund Lee Ellsworth, Brighton, MI (US);
Elizabeth Lunney, Ann Arbor, MI (US);
Bradley Dean Tait, Canton, MI (US);
Assignee:
Warner-Lambert Company, Morris Plains, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; A61K / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
514460 ; 5142278 ; 5142322 ; 514255 ; 514314 ; 514336 ; 514374 ; 514378 ; 514397 ; 514414 ; 514422 ; 514432 ; 514444 ; 514451 ; 514459 ; 549 28 ; 549 60 ; 549292 ; 549293 ; 549294 ; 549426 ; 549427 ; 546135 ; 5462821 ; 544 60 ; 544149 ; 544374 ; 548247 ; 548235 ; 5483111 ; 548465 ; 548509 ; 548517 ;
Abstract
The present invention relates to novel 5,6-dihydropyrone derivatives and related structures which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The 5,6-dihydropyrone derivatives are useful in the development of therapies for the treatment of bacterial and viral infections and diseases, including AIDS. The present invention is also directed to methods of synthesis of multifunctionalized 5,6-dihydropyrones and of related structures.