The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 1998

Filed:

Sep. 05, 1997
Applicant:
Inventors:

Sheo B Singh, Edison, NJ (US);

Russell B Lingham, Watchung, NJ (US);

Keith C Silverman, Somerset, NJ (US);

Deborah L Zink, Manalapan, NJ (US);

Isabel Martin, Madrid, ES;

Fernando Pelaez, Madrid, ES;

Manuel Sanchez, Madrid, ES;

Assignee:

Merck & Co., Inc., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514453 ; 549382 ; 549297 ; 549384 ;
Abstract

The present invention is directed to steroidal or terpenoidal compounds which inhibit farnesyl-protein transferase (FPTase). The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and treatment of cancer.


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