The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 1998

Filed:

May. 03, 1995
Applicant:
Inventors:

Kirk B Jensen, Boulder, CO (US);

Hang Chen, Boulder, CO (US);

Kevin N Morris, Schwarzach, AT;

Andrew Stephens, Denver, CO (US);

Larry Gold, Boulder, CO (US);

Assignee:

NeXstar Pharmaceuticals, Inc., Boulder, CO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H / ; C07H / ; C12P / ; C12Q / ;
U.S. Cl.
CPC ...
435-6 ; 435 912 ; 536 254 ; 935 77 ; 935 78 ;
Abstract

This invention discloses high-affinity oligonucleotide ligands to complex tissue targets, specifically nucleic acid ligands having the ability to bind to complex tissue targets, and the methods for obtaining such ligands. Tissue targets comprise cells, subcellular components, aggregates or cells, collections of cells, and higher ordered structures. Specifically, nucleic acid ligands to red blood cells ghosts, glioblastomas, and lymphomas are described.


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