The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 21, 1998
Filed:
Mar. 04, 1996
Tom Saul, El Granada, CA (US);
Hans O Ribi, Hillsborough, CA (US);
Biocircuits Corporation, Sunnyvale, CA (US);
Abstract
Methods and cartridges are provided for the detection of analytes in a sample by using fluid velocity gradients. In the subject methods, the assay medium is prepared by combining sample suspected of containing analyte with a reagent composition which includes at least one of particles and specific binding pair members ('sbpm's '). A circumferential fluid velocity gradient and vertical fluid velocity gradient are applied to the assay medium to affect the formation of agglutinates. The sizes of the resulting agglutinates are related to the velocity gradients. The level of agglutination is detected to determine analyte presence in the sample. In general, a cartridge for employing the assay comprises two spaced apart parallel plates defining an assay area and trough area there between. A sample port and optically clear window are provided. At least one of the plates is connected to a rotational driver to rotate the plate in a direction counter to the position of the other plate.