The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 21, 1998
Filed:
Apr. 13, 1995
Applicant:
Inventor:
Raymond A Koski, Old Lyme, CT (US);
Assignee:
Amgen Inc., Thousand Oaks, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N / ; G01N / ; C12N / ; C07K / ;
U.S. Cl.
CPC ...
435-723 ; 435330 ; 435331 ; 4353441 ; 435346 ; 435 405 ; 435 4051 ; 435 4052 ; 5303873 ; 5303877 ; 5303879 ; 5303888 ; 53038885 ; 5303913 ;
Abstract
Anti-p185.sup.HER-2/neu antibodies which are useful in the detection of HER-2/neu oncogene overexpression in biological samples are described. The antibodies are accurate and reliable in immunocytochemical or immunohistochemical assays of cell and tissue samples. Also described are methods for detecting HER-2/neu oncogene expression in a biological sample using the antibodies of the invention and a diagnostic kit comprising the antibodies. The reagents provide an accurate means of identifying certain cancer patients who have the greatest probability of relapse and/or the least likelihood of survival.