The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 1998
Filed:
May. 31, 1994
Applicant:
Inventors:
Henk van den Bosch, Maarn, NL;
Gysbert M van Wijk, Utrecht, NL;
Raj Kumar, San Diego, CA (US);
Karl Y Hostetler, Del Mar, CA (US);
Assignee:
NeXstar Pharmaceuticals, Inc., Boulder, CO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H / ; C07F / ; C07F / ; C07F / ;
U.S. Cl.
CPC ...
536 553 ; 536 2671 ; 536 2672 ; 558127 ; 558132 ;
Abstract
A process for the preparation of glycerol di- or triphosphate derivatives comprising coupling the phosphate group of a glycerol monophosphate derivative in which one of the phosphate hydroxyls is replaced by a leaving group, with the terminal phosphate group of a mono- or diphosphate compound or a salt thereof, in the presence of a basic catalyst, under anhydrous conditions.