The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 1998
Filed:
Aug. 21, 1996
Applicant:
Inventors:
Katherine Louisa Widdowson, King of Prussia, PA (US);
Daniel Frank Veber, Ambler, PA (US);
Anthony Joseph Jurewicz, Royersford, PA (US);
Robert Philip Hertzberg, Downingtown, PA (US);
Melvin Clarence Rutledge, Jr, Lansdale, PA (US);
Assignee:
SmithKline Beecham Corporation, Philadelphia, PA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
514311 ; 514369 ; 514445 ; 514586 ; 514597 ;
Abstract
This invention relates to novel compounds and a novel use of phenyl ureas in the treatment of disease scates mediated by the chemokine, Interleukin-8 (IL-8). In particular, this invention relates to the novel compounds of Formula (Ia) and their use in treating chemokine mediated diseases wherein the chemokine binds to an IL-8 a or b receptor. Compounds of Formula (Ia) are represented by the structure: ##STR1## wherein interalia, X is oxygen or sulfur;