The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 1998
Filed:
May. 17, 1996
Applicant:
Inventors:
Allen A Fienberg, New York, NY (US);
Paul Greengard, New York, NY (US);
Assignee:
The Rockefeller University, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C12N / ; A61K / ;
U.S. Cl.
CPC ...
800-2 ; 424-91 ; 424-92 ; 4351723 ; 435325 ; 800-2 ; 800D / ; 800D / ; 800D / ; 800D / ; 935 34 ; 935 70 ;
Abstract
A knockout mouse containing a non-functional allele for the gene that naturally encodes and expresses functional DARPP-32 is disclosed. This mouse contains two non-functional alleles for the gene that naturally encodes and expresses functional DARPP-32, and therefore is unable to express functional DARPP-32. This mouse finds utility as a screening model for potential therapeutic agents useful in the treatment of schizophrenia, Parkinson's disease, and the treatment of addictions, especially those involving drugs of abuse.