The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 07, 1998

Filed:

Jul. 31, 1995
Applicant:
Inventors:

Hashem Akhavan-Tafti, Sterling Heights, MI (US);

Renuka De Silva, Northville, MI (US);

A Paul Schaap, Grosse Pointe Park, MI (US);

Assignees:

Lumigen, Inc., Southfield, MI (US);

Board of Governors Wayne State Univ., Detroit, MI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07C / ; C07F / ;
U.S. Cl.
CPC ...
549332 ; 536-71 ; 560 60 ; 558180 ;
Abstract

Stable, enzymatically triggered chemiluminescent 1,2-dioxetanes with improved water solubility are provided. Dioxetanes further instituted with two or more water-solubilizing groups disposed on the dioxetane structure provide superior performance by eliminating the problem of reagent carryover when used in assays performed on capsule chemistry analytical systems. Compositions comprising a dioxetane with two or more water-solubilizing groups, a non-polymeric cationic surfactant enhancer and optionally a fluorescer, for providing enhanced chemiluminescence are also provided.


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