The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 1998
Filed:
Oct. 10, 1995
Applicant:
Inventor:
Roy Eugene Snoke, Webster, NY (US);
Assignee:
Johnson & Johnson Clinical Diagnostics Inc., Rochester, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N / ; C12Q / ;
U.S. Cl.
CPC ...
435-792 ; 422 56 ; 422 57 ; 435-793 ; 435-794 ; 435-795 ; 435 28 ; 435962 ; 435968 ;
Abstract
Modified apo-peroxidases have been found useful in analytical methods to remove the bias caused by the presence of hemoglobin in the test specimens. While apo-peroxidases are known to remove serum interferents, they fail to overcome the hemoglobin bias, particularly when dry coated analytical elements are used in the assays. Blocking the nitrogen atoms of the imidzolyl groups of the histidine amino acids of the apo-peroxidase prevents catalytic activity of the protein in the presence of hemoglobin.