The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 30, 1998
Filed:
Feb. 05, 1996
Applicant:
Inventors:
Arlindo Lucas Castelhano, New City, NY (US);
Teng Jiam Liak, Mississauga, CA;
Stephen Horne, Burlington, CA;
Alexander Krantz, Menlo Park, CA (US);
Zhengyu Yuan, Fremont, CA (US);
Jian Jeffrey Chen, Santa Clara, CA (US);
Paul David Cannon, San Carlos, CA (US);
Hal Van Wart, Los Altos, CA (US);
Assignee:
Syntex (U.S.A.) Inc., Palo Alto, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514 80 ; 514413 ; 540456 ; 540460 ;
Abstract
Compounds of formula (I): ##STR1## as single stereoisomers or mixtures thereof and their pharmaceutically acceptable salts inhibit matrix metalloproteases, such as interstitial collagenases, and are useful in the treatment of mammals having disease states alleviated by the inhibition of such matrix metalloproteases, for example arthritic diseases or bone resorption diseases, such as osteoporosis.