The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 23, 1998
Filed:
May. 23, 1995
Applicant:
Inventors:
Robert M Hudziak, Corvallis, OR (US);
H Michael Shepard, Rancho Santa Fe, CA (US);
Axel Ullrich, Portola Valley, CA (US);
Brian M Fendly, Half Moon Bay, CA (US);
Assignee:
Genentech, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07K / ; C07K / ; C12P / ;
U.S. Cl.
CPC ...
4241301 ; 4241331 ; 4241341 ; 4241421 ; 4241431 ; 4241551 ; 4241561 ; 4241741 ; 4241831 ; 53038822 ; 5303873 ; 5303877 ; 5303888 ;
Abstract
A method of inhibiting growth of tumor cells which overexpress a growth factor receptor or growth factor by treatment of the cells with antibodies which inhibit the growth factor receptor function, is disclosed. A method of treating tumor cells with antibodies which inhibit growth factor receptor function, and with cytotoxic factor(s) such as tumor necrosis factor, is also disclosed. By inhibiting growth factor receptor functions tumor cells are rendered more susceptible to cytotoxic factors.