The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 16, 1998
Filed:
Jun. 03, 1997
Tadakatsu Mandai, Kurashiki, JP;
Hiroshi Okumoto, Kurashiki, JP;
Koji Hara, Yokohama, JP;
Katsuhiko Mikuni, Yokohama, JP;
Kozo Hara, Yokohama, JP;
Hiroki Hamada, Okayama, JP;
Ensuiko Sugar Refining Co., Ltd., Yokohama, JP;
Tadakatsu MANDAI, Kurashiki, JP;
Kaken Pharmaceutical Co., Ltd., Tokyo, JP;
Abstract
A taxoid derivative wherein sugar is combined with any one of paclitaxel, docetaxel and 10-deacetyl-bacatin III via a spacer. A method of producing the taxoid derivative comprises protecting hydroxyl groups at specific position of paclitaxel or docetaxel by protective compound followed by reacting with tetrabenzyl acetyloxyglucoside, and then carrying out debenzyl and detriethylsilyl reactions. A method of producing the taxoid derivative comprises reacting paclitaxel or docetaxel with tetrabenzyl acetyloxyglucoside, and then carrying out debenzyl reaction.