The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 09, 1998
Filed:
Apr. 04, 1996
Applicant:
Inventors:
Anthony J Conley, Exton, PA (US);
Beth A Arnold, Quakertown, PA (US);
Lynn J Boots, Lansdale, PA (US);
Paul M Keller, Lansdale, PA (US);
Assignee:
Merck & Co., Inc., Rahway, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07K / ; C07K / ;
U.S. Cl.
CPC ...
530326 ; 530350 ; 530395 ; 4241881 ; 4241841 ; 4242081 ; 4242041 ;
Abstract
Immunological conjugates of HIV-specific selected principal neutralization epitopes are prepared. These epitopes bind 19b, a broadly neutralizing human monoclonal antibody specific for the HIV gp120. The epitopes are identified from oligopeptide epitope libraries. The conjugates are useful for vaccination against AIDS or ARC, as well as in the production of other HIV-specific broadly neutralizing antibodies for passive immunity against AIDS or ARC.