The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 02, 1998

Filed:

Dec. 24, 1996
Applicant:
Inventors:

Francesco Santangelo, Milan, IT;

Mario Fantucci, Milan, IT;

Claudio Semeraro, Bresso, IT;

Franco Pellacini, Milan, IT;

Stefano Romagnano, Buccinasco, IT;

Gabriele Norcini, Vizzola Ticino, IT;

Assignee:

Zambon Group S.p.A., Milan, IT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ;
U.S. Cl.
CPC ...
548204 ; 514365 ; 514369 ; 514370 ; 514372 ; 548182 ; 548205 ; 548214 ;
Abstract

Compounds of formula ##STR1## wherein R, R.sub.1, R.sub.2, R.sub.3, R.sub.4, m and n have the meanings reported in the description, processes for their preparation and pharmaceutical compositions which contain them as active ingredients are described. The compounds of formula I are endowed with a mixed ACE-inhibitory and NEP-inhibitory activity and are useful in the treatment of cardiovascular diseases.


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