The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 02, 1998

Filed:

Sep. 20, 1994
Applicant:
Inventors:

Rony Tal, Richmond, CA (US);

David H Gelfand, Oakland, CA (US);

Roger D Calhoon, San Diego, CA (US);

Arie Ben-Bassat, Gainesville, FL (US);

Moshe Benziman, Jerusalem, IL;

Hing Cheung Wong, San Ramon, CA (US);

Assignee:

Weyerhaeuser, Federal Way, WA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C12N / ; C12P / ;
U.S. Cl.
CPC ...
4351723 ; 435 691 ; 435 711 ; 435170 ; 435199 ; 435232 ; 4353201 ; 935-9 ; 935 11 ; 935 66 ; 935 72 ; 935 73 ; 536 231 ; 536 232 ; 536 237 ;
Abstract

The present invention provides the nucleotide sequences of Acetobacter operons, cdg operons encoding genes for the biosynthesis and degradation of cyclic diguanosine monophosphate (c-di-GMP). Specifically, the nucleotide sequences and deduced amino acid sequences of 3 phosphodiesterases isozymes, 3 diguanylate cyclase isozymes, and 2 polypeptides of unidentified function are provided. Also provided for are various strains of microorganisms, including Acetobacter cells genetically manipulated so as to produce elevated and/or reduced levels of one or more cdg operon encoded proteins.


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