The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 1998
Filed:
Oct. 05, 1989
Applicant:
Inventors:
Noboru Maki, Iruma-gun, JP;
Shintaro Yagi, Iruma-gun, JP;
Kazuya Watanabe, Iruma-gun, JP;
Masanori Suzuki, Iruma-gun, JP;
Assignee:
Tonen Corporation, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12D / ; C12D / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435 691 ; 435 698 ; 435 711 ; 4352552 ; 4353201 ; 935 11 ; 935 60 ;
Abstract
A process for the production of human serum albumin A (HSA) characterized by culturing host cells transformed with the plasmids containing a leader DNA sequence and a cDNA coding for mature HSA to produce and secrete mature HSA, and recovering the mature HSA. As the leader HSA sequence, a cDNA coding for the prepro sequence of HSA, a synthetic DNA coding for the prepro sequence of HSA, by the codons frequently used in a selected host, a DNA coding for a chimeric leader peptide, a DNA coding for MF.alpha.1 prepro sequence, or a DNA coding for PH05 signal peptide, is used.