The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 26, 1998

Filed:

Nov. 15, 1996
Applicant:
Inventors:

Karel R Schubert, Norman, OK (US);

Ulrich Reimann-Philipp, Norman, OK (US);

Thomas H Czapla, Urbandale, IA (US);

Harold B Rathburn, Stephenville, TX (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07K / ; C07K / ; C07K / ;
U.S. Cl.
CPC ...
530300 ; 514-2 ;
Abstract

The invention comprises a leucine aminopeptidase inhibitor (LAPI) having hemagglutination activity which is extracted from the seeds of Pentaclethra macroloba. The crude extract was found to comprise an active species having a molecular weight in the range 1.5-60 kilodaltons and further comprises an amino acid containing component, a fluorescent component and sugars. The basic unit of the active species contains approximately the following type and number of amino acid residues averaged over a plurality of separations and analyses: 3 aspartate, 3 threonine, 4.5 serine, 3.75 glutamic, 6.5 glycine, 3.5 alanine, 2.25 valine, 1.25 isoleucine, 2 leucine, 0.75 tyrosine, 1.25 phenylalanine, 5.25 lysine, 0.75 histidine, 2.25 arginine and 0.625 proline, and forms multimers, adduct, conjugate and similar species between by itself or with proteinaceous, fluorescent and sugar substance which may also be present. The active substance(s) act as an insecticide and have been found to increase insect mortality in bioassays. The active substance(s) are particularly effective against European corn borer larvae.


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