The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 26, 1998
Filed:
Jun. 28, 1996
Applicant:
Inventors:
Haruo Onda, Tsukuba Ibaraki, JP;
Shoichi Ohkubo, Tsukuba Ibaraki, JP;
Takuo Kosaka, Tsukuba Ibaraki, JP;
Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
4352523 ; 435 694 ; 435325 ; 43525233 ; 4353201 ; 530324 ; 530315 ; 536 2351 ;
Abstract
Disclosed are (1) a DNA containing a cDNA segment coding for human endothelin-2 (SEQ ID NO:1), (2) a precursor of human endothelin-2 (SEQ ID NO:2), (3) a transformant carrying a DNA containing a cDNA segment coding for human endothelin-2, and (4) a method for preparing mature human endothelin-2 which comprises culturing the transformant described in (3), accumulating a protein in a culture medium, and collecting the same, whereby human endothelin-2 and the precursors thereof can be produced in large amounts.