The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 19, 1998

Filed:

Sep. 06, 1996
Applicant:
Inventors:

Masahide Hoshino, Ichikai-machi, JP;

Hiroshi Kusuoku, Ichikai-machi, JP;

Tadashi Hase, Ichikai-machi, JP;

Atsuko Otsuka, Ichikai-machi, JP;

Ichiro Tokimitsu, Ichikai-machi, JP;

Akira Yamamuro, Ichikai-machi, JP;

Yoshiya Sugai, Ichikai-machi, JP;

Koji Yoshino, Ichikai-machi, JP;

Youichi Arai, Ichikai-machi, JP;

Shinichi Meguro, Ichikai-machi, JP;

Assignee:

Kao Corporation, Tokyo, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; C07C / ;
U.S. Cl.
CPC ...
514616 ; 514847 ; 514463 ; 5142312 ; 564160 ; 564159 ; 564152 ; 424401 ; 560250 ; 554 57 ; 554 61 ; 554 66 ; 549452 ; 544175 ;
Abstract

An amide derivative represented by the following formula (1): ##STR1## wherein R.sup.1 represents a C.sub.1-40 hydrocarbon; R.sup.2 represents a C.sub.1-6 alkylene; R.sup.3 represents H, OH or alkoxyl; R.sup.4 represents a C.sub.1-39 hydrocarbon; R.sup.5 represents ##STR2## with the proviso that when R.sup.5 represents ##STR3## R.sup.3 does not represent OH; and a composition of the amide derivative for topical application to human skin. The composition improves the barrier function of the stratum corneum, providing improvement and prevention of dermatitis, skin roughness, or similar disorders.


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