The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 19, 1998

Filed:

Mar. 26, 1997
Applicant:
Inventors:

Shinichiro Ono, Hirakata, JP;

Tomohiro Yoshida, Hirakata, JP;

Atsuyuki Ashimori, Hirakata, JP;

Keigo Kosaka, Hirakata, JP;

Takehiro Okada, Hirakata, JP;

Kazuhiro Maeda, Hirakata, JP;

Masahiro Eda, Hirakata, JP;

Fumio Mori, Hirakata, JP;

Yoshihisa Inoue, Hirakata, JP;

Hajime Ebisu, Hirakata, JP;

Teruaki Imada, Hirakata, JP;

Ruriko Ikegawa, Hirakata, JP;

Feng Wang, Hirakata, JP;

Norifumi Nakamura, Hirakata, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514300 ; 514211 ; 514301 ; 514302 ; 540597 ; 546113 ; 546114 ; 546115 ;
Abstract

A novel carboxylic acid compound having a condensed ring; which is represented by the formula (I) ##STR1## wherein each symbol is as defined in the specification, a pharmacologically acceptable salt thereof, a pharmaceutical composition thereof and pharmaceutical use thereof. The novel carboxylic acid compound having a condensed ring and pharmacologically acceptable salt thereof of the present invention have superior GPIIb/IIIa antagonism in mammals inclusive of human; can be administered orally; have long life in blood and low toxicity; and show less side-effects. Accordingly, they are extremely useful for the prophylaxis and treatment of thrombotic diseases and other diseases.


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