The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 12, 1998
Filed:
Nov. 05, 1996
Stephanus Francois Marais, Garsfontein, ZA;
Thebeeapelo John Khaile, Erasmuskloof, ZA;
Owen Lungile Njamela, Kempton Park, ZA;
Dana Helen Braithwaite, Johannesburg, ZA;
Deborah Nicole Davidson, Hurlyvale, ZA;
Christa Maria Jungmann, Edenvale, ZA;
Christopher John Parkinson, Modderfontein, ZA;
Neil Stockenstrom Gardiner, Noordwyk, ZA;
Lucia Hendrina Steenkamp, Boksburg, ZA;
Etienne Van Eeden Skein, Randburg, ZA;
AECI Limited, Johannesburg, ZA;
Abstract
A process for the production of disubstituted propionic acid derivatives which are intermediates in the synthesis of .alpha.-arylpropionic acids such as naproxen, involves the reaction of a naphthalene derivative such as 2-methoxynaphthalene, with an alkylating agent such as an alkyl pyruvate in the presence of a catalyst, and then dehydrating and hydrogenolising, or directly hydrogenolising, or derivatising and then hydrogenolising the product thereof, to produce the desired compound.