The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 12, 1998
Filed:
Oct. 15, 1996
Charles G Caldwell, Scotch Plains, NJ (US);
Ping Chen, Old Bridge, NJ (US);
Philippe L Durette, New Providence, NJ (US);
Paul Finke, Milltown, NJ (US);
Jeffrey Hale, Westfield, NJ (US);
Edward Holson, New York, NY (US);
Ihor Kopka, Millburn, NJ (US);
Malcolm MacCoss, Freehold, NJ (US);
Laura Meurer, Scotch Plains, NJ (US);
Sander G Mills, Woodbridge, NJ (US);
Albert Robichaud, Stirling, NJ (US);
Merck & Co., Inc., Rahway, NJ (US);
Abstract
The present invention is directed to certain novel compounds represented by structural formula I: ##STR1## or a pharmaceutically acceptable salt thereof, wherein R.sup.3, R.sup.6, R.sup.7, R.sup.8, R.sup.11, R.sup.12, R.sup.13, A, Q, W, X, Y, Z and n are defined herein. The invention is also concerned with pharmaceutical formulations comprising these novel compounds as active ingredients and the use of the novel compounds and their formulations in the treatment of certain disorders. The compounds of this invention are tachykinin receptor antagonists and are useful in the treatment of inflammatory diseases, pain or migraine, asthma and emesis.